Kim, S. H. et al. Large-scale femtoliter droplet array for digital counting of single biomolecules. Lab Chip 12, 4986–4991 (2012).

To investigate the potential of surface energy patterned microwells for digital bead-based bioassays, we seeded well arrays with magnetic beads (Fig. 3). All CA combinations were sufficient for bead seeding in surface energy patterned microwells, allowing minimizing the RIM incubation time. Digital counting of the magnetic beads revealed seeding efficiencies as high as 75.1 ± 6.0% for single-step seeding and 87.2 ± 0.3% for multiple-step seeding (Fig. 3b, Table S2).

Legacy Precision Molds takes us on a tour of their moldbuilding facility. They've recently implemented two automated 5-axis cells for metal and graphite machining that run lights out during nights and weekends.

Microstructured surfaces and microfluidic components are increasingly important for a diverse range of biological and clinical applications, e.g., in protein and cell studies1,2,3. Using polymers for such applications is often preferred over glass or silicon because of the soft material properties and the ease of device replication. Whereas micro-injection molding (IM) and micro-reaction injection molding (RIM) enable industrial-scale microstructuring of low-cost polymer materials4, the lack of a simple and straightforward approach for surface modification remains a limiting factor5. Microscale hydrophilic and hydrophobic patterning is commonly achieved via back-end processing techniques, e.g., plasma treatment, grafting and chemical coating6,7, which are multi-step, cumbersome, and subject to degradation over time8. Furthermore, surface modification of 3D patterns and control over surface topography remain unresolved challenges.

Chiron Group combines the best of both worlds at IMTS 2024, featuring live demonstrations of their Micro5 and Mill 2000 machines, alongside a cutting-edge virtual showroom. This innovative approach allows visitors to explore Chiron’s full product lineup without the logistical challenges of transporting large equipment.

Each tool setting technique has merit, and it depends on where you are as a shop and the type of work you do, as cost and efficiency all come into play.

Looking to automate your shop floor? The Automated Shop Conference (TASC) will connect shops with experts who can advise them through this transition.

FANUC’s IMTS 2024 booth includes real-time demonstrations that show the abilities of its equipment, including robots, controllers and machine tools.

Mitsui Seiki USA Inc. appoints Joseph Farkas as its director of sales West and Terry Ritterbush as its director of sales East.

Supplementing CNC connections with sensors and machine learning enables predicting performance on the level of the individual part.

The CA measurements demonstrate the surface energy pattern replication. The reduced concentration of hydrophilic or hydrophobic moieties resulted in microstructured replicas with excellent functionality, but also in a dependence of the hydrophobic mimicking phenomenon on the incubation time. Nevertheless, even at zero incubation time, the hydrophobic surfaces feature an equilibrium CA equal to 90°, which proved sufficient for bead seeding and well sealing. Although the degree of hydrophilicity associated to the replica is lower than that of glass, it is sufficient for droplet entrapment inside the microwells. The CA on the hydrophobic polymer surface did not change significantly during long-term storage; that of the hydrophilic surface reduced from 59.3 ± 2.6° to 48.1 ± 2.2°. We attribute this increase of hydrophilicity to oxidation of the thiol groups when exposed to the ambient air28. Compared to postprocess surface modification techniques such as plasma treatment of PDMS, which is prone to fast recovery of surface energy, our method offers a far more stable surface energy definition with some degree of enhancement regarding the hydrophilic surfaces over time.

When revising part designs, investigate the 3D CAD, the 2D drawing and the part’s functional requirements to determine which details should be tightened up.

Understanding all the things that contribute to a machine’s full potential accuracy will inform what to prioritize when fine-tuning the machine.

Misapplication of these important CNC features will result in wasted time, wasted or duplicated effort and/or wasted material.

In the latest episode of our View From My Shop series, MMS Editor-in-Chief Brent Donaldson visited the JN Shapiro Watches headquarters and production facility where Founder Joshua Shapiro—a history teacher turned watchmaker—realized his dream of "making a watch from scratch and everything in it."

The high-seeding efficiency reported here is ascribed to the successful surface energy patterning of the arrays and is of significance for bead-based bioassays, which require rapid and efficient bead seeding. Our results compare well with the estimated 40–50% gravity-based bead loading efficiency achieved in the SIMOA process16 and the maximum 35% efficiency obtained in previously reported single-step seeding12.

Here, we demonstrate a molding technique capable of microstructuring and 3D in situ surface energy patterning in a single step. We use this platform for high-throughput, scalable replication of HIH femtolitre-well arrays and demonstrate a record-high seeding efficiency of magnetic beads in femtolitre-well arrays.

The choice between buying a new machine or refurbishing the current one will become clear after a thorough assessment of the machine.

Figure 1 illustrates the specifically developed mold fabrication process, the replication process that combines RIM of OSTE with area-selective monomer self-assembly, and the resulting replicas and their surface energies. We developed a two-part HIH mold consisting of a milled Al half with good thermal conductivity, and a UV transparent microstructured half consisting of fused silica and TeflonTM. Using a hard mask is compatible with industrial injection molding settings in which a material of high Young-modulus circumvents the deformation and collapse of delicate microscale mold features. This is in contrast to use of PDMS, a prevalent material of choice in academia, which is prone to deformation and subsequent feature distortion during the molding process and therefore not easily applicable to commercial set-ups.

Walter USA has acquired PDQ Workholding, intending to strengthen its offering of workholding products and develop future cutting tool sales.

So far, Made in the USA has looked into system-wide effects of broken supply chains, automation, skilled workforce issues and our perception of manufacturing jobs — examining each topic through a prism of individual experiences. For this final episode for Season 1, let’s look at one more system-wide question and bring it back to personal perspectives: Is there today a new dawn, a new moment for American manufacturing?

Hydrophilic-in-hydrophobic (HIH) femtolitre-well arrays for digital bioassays are an example of structures that would greatly benefit from simpler fabrication techniques. Digital bioassays commonly exploit arrays of microwells as their hardware and can extensively benefit from selective surface energy patterning9. In such systems, the sample of interest is compartmentalized in well reactors amenable to high-throughput screening or online monitoring10. Such systems enable the ultra-sensitive detection of target molecules on a single-molecule level11. A common solution for efficient isolation of wells is to provide hydrophilic wells in a hydrophobic field. In bead-based digital assays, each well acts as a microchamber that traps a single bead functionalized with bioreceptors and surrounded by a micro-droplet of reagent. Femtolitre-well arrays for bead seeding in digital bioassays were previously fabricated mainly using cleanroom-based techniques9,12,13,14, poly(dimethylsiloxane) (PDMS) stamp imprinting15, or IM16,17. However, these materials and fabrication methods are expensive, not scalable, or do not result in defined surface energy features, the latter resulting in an inefficient bead seeding, leading to limited assay performance18.

Chiron Group combines the best of both worlds at IMTS 2024, featuring live demonstrations of their Micro5 and Mill 2000 machines, alongside a cutting-edge virtual showroom. This innovative approach allows visitors to explore Chiron’s full product lineup without the logistical challenges of transporting large equipment.

Machado, T. O., Sayer, C. & Araujo, P. H. H. Thiol-ene polymerisation: a promising technique to obtain novel biomaterials. Eur. Polym. J. 86, 200–215 (2017).

Tool-holder-spindle-machine combinations each have a unique dynamic response in the same way that each person has a unique fingerprint, which can be revealed using modal testing.

The RIM process is illustrated in Fig. 1g–j. A 5 mL syringe was filled with OSTE precursor, equipped with a 1.20 mm by 40 mm Sterican blunt needle and actuated to purge air bubbles from the tip of the syringe and needle. The needle was fitted to the inlet tube, and the syringe was slowly actuated to inject the precursor into the cavity. To allow for shrinkage compensation during curing, we adjusted the volume of precursor injected to include the volume of the entire mold chamber and part of the outlet channel. We, thereafter, removed the syringe and needle. The hydrophilic and hydrophobic moieties in the precursor self-assembled on mold surfaces with matching surface energy, i.e., hydrophilic moieties self-assembled on pillars, resulting in hydrophilic replica surfaces in the wells, and hydrophobic moieties self-assembled on the Teflon substrate, resulting in a hydrophobic top surface of the replicas. We performed experiments in which we allowed incubation of the precursor in the setup for up to 60 min, while shielding from UV light, to allow the hydrophilic and hydrophobic moieties to diffuse to surfaces of the mold with matching surface energies. Thereafter, the precursor was cured for 15 s at 12.5 mW/cm2. After curing, we separated the mold halves using a custom demolding fixture consisting of four ejection pins and removed the replica from the mold using tweezers.

The RIM setup is comprised of two mold halves which come together to form the negative shape of the final chip. The first mold half is a 5 mm thick Al sheet (4.5 × 7.4 cm2) CNC milled (MiniMill GX, Minitech Machinery Corp., USA) with a 3.5 × 3.5 cm2 indentation to form a cavity. Inlet and outlet channels connect the cavity to the edges of the mold.

Q-Mark has built its metrology business by providing what customers need, when they want it. This goes for its IMTS booth, too, with free drinks alongside custom technology.

For its connected machines, EPTAM still relies on Datanomix Benchmarks (formerly known as Fusion Factors), which rate each machine’s productivity according to a benchmark that constantly recalibrates in response to real machining performance, but the facility now combines this information with data about product movement and cost breakdowns from EPTAM’s ERP software. Datanomix then turns this combination of ERP data and machine monitoring data into a Daily Operations Report analyzing each day’s production, broken down by value streams and departments throughout EPTAM. Plant Operations Manager Jesse Bunnell says that data should correlate between the ERP and Datanomix sides of the report. “If there is not a direct correlation, that is a red flag,” he says. “The appropriate leaders or managers make a note of it and take action.”

Through its years of using Datanomix, EPTAM Precision Plastics has relied on the software’s utilization benchmarking features. When performance regularly drops in comparison to a senior machinist’s initial run, the shop knows to focus on that area for continuous improvement projects. Images courtesy of Datanomix.

Join Mahr for an informative webinar to discover the latest advancements in precision measurement, designed to elevate your quality assurance processes and unlock peak productivity. It'll explore cutting-edge technologies — such as modern height gages and contour measuring systems — along with their applications, benefits and technical capabilities. Discover the power of height gages: Learn how intuitive and sophisticated height gages can revolutionize your measurement processes, enabling quick and accurate results in inspection and production areas. Explore the practical functions and ease of use that make height gages an ideal solution for manufacturers seeking high-performance and reliable measuring technology. Examine sample applications and industries where height gages excel, such as qualifying first parts, inspecting incoming parts and measuring series of parts in industries like aerospace, automotive and medical. Unlock efficient contour measurement: An introduction to the latest contour measuring technologies that enable fast, simple and comprehensive contour measurement in the production environment. Discover how these innovative solutions ensure reliable measurements, saving time and increasing efficiency while measuring a wide range of workpieces. Learn how to streamline your contour measuring process with speed and simplicity, achieving fast and precise measurements with incredible versatility. Register now and discover how to unlock peak productivity with new innovations in precision measurement. Agenda: Insights into the latest precision measurement technologies and their applications Understanding of how to improve quality assurance processes and increase productivity Knowledge of how to select the right measurement solutions for your specific needs Tips on how to optimize your measurement processes for maximum efficiency

We dragged a 30 μL droplet of a 0.25 mg/mL fluorescein solution (Sigma-Aldrich, Belgium) over the microwell array. We subsequently covered the droplet of fluorescein with a 180 μL droplet of PlusOne Drystrip Coverfluid oil (Sigma-Aldrich, Belgium) to prevent evaporation. Next, we removed the fluorescein from underneath the oil using a glass pipette tip, first dragging the fluorescein droplet away from the array, then pipetting the fluorescein out from underneath the oil. The sealed microwells were visualized using an inverted fluorescence microscope (Nikon TiEclipse, Japan), using a TITC filter (excitation 465–495 nm, emission 515–550 nm).

Okuma America Corp. announces its plans to create a global service and repair facility, set to open in Charlotte, North Carolina, in 2025.

AccuRounds has created synergy between culture and technology, driving a commitment to customer satisfaction and continuous improvement.

There are usually better solutions to chatter than just reducing the feed rate. Through vibration analysis, the chatter problem can be solved, enabling much higher metal removal rates, better quality and longer tool life.

Becker, H. & Gärtner, C. Polymer microfabrication technologies for microfluidic systems. Anal. Bioanal. Chem. 390, 89–111 (2008).

Take a look inside James Engineering, a high-end CNC Deburring OEM that became a job shop when they decided to produce their own parts in-house.

Misapplication of these important CNC features will result in wasted time, wasted or duplicated effort and/or wasted material.

Rastogi, A., Paik, M. Y., Tanaka, M. & Ober, C. K. Direct patterning of intrinsically electron beam sensitive polymer brushes. ACS Nano 4, 771–780 (2010).

Heckele, M. & Schomburg, W. K. Review on micro molding of thermoplastic polymers. J. Micromech. Microeng. 14, R1 (2003).

a Schematic of the magnetic bead seeding on HIH microwell arrays. b The bead distribution in arrays with well diameter 3.5 μm and with varying array pitch and well depth, for single- and multiple-seeding cycles (n = 5). Dots indicate results from each experiment; columns indicate the average ratio of wells that contain a given number of beads; error bars mean ± s.d. c, d ×40 magnification bright field microscopy image of a microwell array before and after magnetic bead seeding, respectively. Bright spots indicate empty microwells and dark spots indicate filled microwells. e ×100 magnification bright field microscopy image of a microwell array after seeding, where one well is empty (bright), two wells contain two beads, and all other wells contain one bead

N. Sandström, et al. Reaction injection molding and direct covalent bonding of oste+ polymer microfluidic devices. J. Micromech. Microeng. 25, 75002–75014 (2015).

Lee Wimmer invited us to tour his second-generation family-owned machine shop in Perkasie, PA. This video explores the production processes behind precision-machined parts for both Wimmer Custom Cycle and LS Wimmer Machine Co., and shows how ingenuity and determination are still at the heart of American manufacturing. Today, both companies are now managed by Wimmer’s three sons.

Though most frequently used for diameter measurements, an air plug and platen can be readily configured to measure perpendicularity.

Hoyle, C. E., Lee, T. Yeon & Roper, T. Thiol–enes: chemistry of the past with promise for the future. J. Polym. Sci. Part A 42, 5301–5338 (2004).

Pardon, G., Haraldsson, T. & van der Wijngaart, W. Simultaneous replication of hydrophilic and superhydrophobic micropatterns through area-selective monomers self-assembly. Adv. Mater. Interfaces 3, 1600404–n/a (2016). 1600404.

Manufacturers continue to feel the pressure to reduce costs, increase efficiencies and meet their sustainability strategies. As the industry evolves to keep pace with these priorities, there are opportunities within metalworking processes to use less resources with advanced lubricants and technical expertise. Agenda:  An overview of metalworking lubrication Evolutions in metalworking lubrication Experience on the shop floor Key takeaways

We express our gratitude to Mercene Labs, Sweden, for their kind contribution of OSTE polymer. We would also like to thank Cecilia Aronsson and Mikael Bergqvist for their contribution to the technical aspects of the research. We furthermore would like to acknowledge Prof. Paula Moldenaers of the Soft Matter, Rheology and Technology group at KU Leuven (Belgium) for providing the facilities for the contact angle measurements and Prof. Michael Kraft of the MICAS group at KU Leuven (Belgium) for providing the facilities for the 3D optical profile measurements. This work was financially sponsored, in part, by the European Union and EFPIA through the IMI project RAPPID and by the European Union through the FP7 project NOROSENSOR. This work has also received funding from Research Foundation-Flanders (FWO SB/1S30116N).

Modern Machine Shop is the leading publication and media brand in North America devoted to CNC machining. MMS combines unprecedented editorial access to manufacturing facilities with decades of experience to provide long-form content that is both insightful and impactful. About Us

Yatsushiro, S. et al. Application of a cell microarray chip system for accurate, highly sensitive, and rapid diagnosis for malaria in uganda. Sci. Rep. 6, 30136 (2016).

Standards for surface finishes and profiles are not static; they change as technology changes or new processes come along that need to be considered.

Rondelez, Yannick et al. Microfabricated arrays of femtoliter chambers allow single molecule enzymology. Nat. Biotechnol. 23, 361 (2005).

We purchased the following monomers and initiator from Sigma-Aldrich, Germany: pentaerythritol tetrakis(3-mercaptopropionate) (PETMP), 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TATATO), 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl methacrylate (FDMA), 2-hydroxyethyl methacrylate (HEMA), and photo-initiator 1-hydroxycyclohexyl phenyl ketone (Irgacure 184). We synthesized the OSTE precursor with excess of allyl functional groups with the following subsequent steps: (i) mixing the allyl monomer TATATO with the photo-initiator (52.32 and 0.5 wt% of the final mixture, respectively), (ii) heating the mixture to 75 °C for 10 min to facilitate the dissolution of the solid photo-initiator, (iii) adding the thiol monomer PETMP (47.08 wt% of the final mixture), (iv) mixing and subsequent degassing, (v) adding HEMA and FDMA, both at 0.05 wt%, and (vi) mixing again.

When it comes to utilizing the spindle’s power, there is a lot of headroom at the upper limits, provided it’s in short bursts. Be mindful of your time at these loads so you don’t stall out.

Heidenhain and Acu-Rite Solutions are offering several hands-on experiences at their booth this year, as well as internal components that reduce energy use.

FANUC’s IMTS 2024 booth includes real-time demonstrations that show the abilities of its equipment, including robots, controllers and machine tools.

That “action” can take many forms but usually requires examining data from Datanomix in further detail. Key to dealing with unexpected downtime is the software’s Downtime Insights feature, which categorizes downtime reasons without requiring operator input. Bunnell says the facility’s most common downtime cause is a “missing operator” as the machine waits for an operator to clear chips or verify an alert. This alert can be especially difficult to solve for second and third shifts, which Bunnell says the facility has not been able to fully staff.

The granularity of Datanomix’s reports has also come in handy for EPTAM as it qualifies the repeatability of its parts. Bunnell cites a recent project that required operations qualification and performance qualification, noting that “if we see some anomalies in the metrology side of this product, we can actually cross-reference that to when these parts had run on the machine and see if there was something happening in the machine. For example, if we look back at the data and Datanomix says the machine sat for 15 minutes — and that machine does not have thermal compensation,” then EPTAM can take steps to ensure that machine is properly warmed up before cutting operations.

Horn USA’s new booth concept is designed to enable attendees to (literally) get a better feel for its various tooling offerings.

Whereas even the most productive machining groups at the facility averaged around 65% productivity before the introduction of robots, machine groups paired with optimized robots see reduced staff strain and can perform weekend operations, leading to about 78% utilization.

Zandi Shafagh, R., Decrop, D., Ven, K. et al. Reaction injection molding of hydrophilic-in-hydrophobic femtolitre-well arrays. Microsyst Nanoeng 5, 25 (2019). https://doi.org/10.1038/s41378-019-0065-2

a–e Schematic of the RIM replication using area-selective monomer self-assembly (g–k); and the resulting structures and surface energies (f, l–n). Blue color indicates hydrophilic surfaces; red color hydrophobic surfaces. a Fused silica substrate (blue) coated with Cr (gray) and photoresist (yellow). b Patterned Cr after photolithography and wet etching. c Fused silica pillars with Cr on top after dry etching. d Fused silica pillars with Cr and Teflon on top after Teflon (red) coating. e Finalized mold with hydrophilic pillar arrays in hydrophobic background after Cr lift-off. f Perspective SEM image of a mold insert with 3.5 μm diameter micropillars. g Mold assembly and precursor injection. h The area-selective self-assembly of monomers on mold surfaces with corresponding surface energy. i UV-curing. j Replica demolding. k Detail of HIH wells in the replica. l Top view SEM image of replicated HIH wells with 3.5 μm diameter and 8.5 μm pitch. m, n Contact angle measurements on corresponding hydrophobic and hydrophilic surfaces of non-structured polymer parts after 60 min incubation time

Working closely with customers and making careful investments has enabled this Wisconsin machine shop to tackle difficult jobs with tight deadlines as a core part of its business.

In conclusion, this work introduces reaction injection molding as a scalable platform suitable for use both in high-throughput and cost-effective manufacturing and in laboratory settings. We demonstrate the technique for the replication of microwell arrays. The distinct feature of simultaneous molding and surface energy patterning results in the structuring of hydrophilic-in-hydrophobic femtolitre well arrays capable of magnetic bead seeding with efficiencies of 75.1% and 87.2% for single-cycle and multiple-cycle seeding, respectively. This technology can pave the road towards successful commercialization of digital-based bioassays, specifically, and is amenable to diverse adaptations in medical devices and life science tools, where the spatial control of surface topology and properties is critical.

Each tool setting technique has merit, and it depends on where you are as a shop and the type of work you do, as cost and efficiency all come into play.

EPTAM does not directly quote through Datanomix, but by inputting the quote from its quoting software, Datanomix can analyze productivity and determine cycle time targets for profitability. The software can perform this analysis midway through a job, enabling the company to make changes partway through a day instead of only catching issues after the accounting department reviews the completed job. If the shop is unable to meet a quote after dialing in machining parameters through the After Action Report, EPTAM then drills down to see if there is a misquote or a misunderstanding about machining capabilities.

“To assume it’s a people issue out of the gate is just not a good way to conduct business,” Bunnell says. With EPTAM’s growth continuing at its meteoric pace, this philosophy appears to be correct.

Consistency is key for beryllium manufacturing, so the data visibility granted by Harmoni has swiftly become a vital, profitable tool in the shop’s arsenal.

Viewing with a ×40 objective allowed scanning a large area and distinguishing wells with and without beads, but did not allow distinguishing between wells with a single and those with multiple beads. At ×100 magnification it was feasible to distinguish between wells with zero, a single or two beads.

Tool-holder-spindle-machine combinations each have a unique dynamic response in the same way that each person has a unique fingerprint, which can be revealed using modal testing.

Certain “hybrid” machines combine some form of additive manufacturing with CNC subtractive manufacturing. Columnist Mike Lynch, President of CNC Concepts Inc., explores three types of these machines here.

Working closely with customers and making careful investments has enabled this Wisconsin machine shop to tackle difficult jobs with tight deadlines as a core part of its business.

In the latest episode of our View From My Shop series, MMS Editor-in-Chief Brent Donaldson visited the JN Shapiro Watches headquarters and production facility where Founder Joshua Shapiro—a history teacher turned watchmaker—realized his dream of "making a watch from scratch and everything in it."

We purchased streptavidin-coated LodeStar 2.7 μm superparamagnetic beads with a stock concentration of 8 × 108 beads/mL from Agilent Technologies (Santa Clara, CA, USA). To prepare the beads for seeding, 10 µL of the stock solution was washed three times in 150 μL of a mixture of phosphate-buffered saline (PBS), 0.1% bovine serum albumin, and 0.1% Tween-20. The beads were resuspended in 80 μL PBS containing 2% Tween-20. For multiple seeding events, we pipetted a 5 μL drop of this solution on the microwell array, and a plastic pipette tip was used to move the droplet back and forth across the array 30 times while a magnet was held underneath the array to attract the beads into the wells. After the 30 seeding events, we removed the magnet and pushed the droplet off of the array. In the case of a single seeding event, we moved the droplet across the array only once. We visualized the beads using an inverted fluorescence microscope in bright field mode (Nikon TiEclipse, Japan) and counted for five different samples.

Madaan, N., Romriell, N., Tuscano, J., Schlaad, H. & Linford, M. R. Introduction of thiol moieties, including their thiol–ene reactions and air oxidation, onto polyelectrolyte multilayer substrates. J. Colloid Interface Sci. 459, 199–205 (2015).

The MB45 series is designed to deliver the low cutting force benefits of positive inserts and the fracture resistance of negative inserts.

The dimensions of the demonstrated microwells are tailored to host a single magnetic bead with 2.7 μm diameter. Not to undermine the true digital nature of the assay, wells containing more than one bead must be excluded from the signal count during the image analysis, and their number should therefore remain limited. For well arrays with 8.5 μm pitch, we estimate trapping two beads in as little as 2.1 ± 0.4% of the wells after single-step seeding, and in 7.1 ± 0.8% after multiple-step seeding (Fig. 3e).

Take a look inside James Engineering, a high-end CNC Deburring OEM that became a job shop when they decided to produce their own parts in-house.

Rissin, D. M. et al. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. Nat. Biotechnol. 28, 595 (2010).

Future work should examine the potential of RIM-based microwell arrays for digital bioassays aiming for single molecule detection. Furthermore, translating the current technology to industrial RIM standards needs a re-adjustment of the mold material, mold cleaning protocols, injection settings, and demolding.

Incremental mode can be more advantageous when programming sculptured surfaces or for certain hole-machining canned cycle applications.

a Schematic of fluorescein and oil stacked on top of HIH microwells followed by the fluorescein removal. b Schematic of the resulting femtolitre fluorescein microdroplets trapped inside the wells. c Top view fluorescence microscopy image of fluorescein microdroplets inside HIH femtolitre-wells: the dark region in the top half of the image has been only in contact with oil whereas the lower half of the image is printed by the receding fluorescent droplet. The dashed line indicates the border of the fluorescein droplet shown in (a)

Ever wonder what sets Top Shops apart from the competition? Dive into their award-winning practices and explore behind-the-scenes strategies for operational excellence.

Automation is no longer a luxury in manufacturing today – it’s a necessity. The Automated Shop Conference (TASC) will connect job shops with experts who offer advice and considerations for this process.

Women in Manufacturing is excited to announce that the 2024 SUMMIT will be a hybrid event — both an in-person and virtual experience. Both program offerings will enable you to grow through education and connections that are insightful, meaningful and actionable. Join Women in Manufacturing Oct. 6-9, 2024, in Boston or digitally for an event filled with plant tours at leading manufacturing facilities, professional development sessions, roundtable discussions on important topics, and inspiring keynotes.  All while engaging and interacting with peers through social and networking events! __PRESENT __PRESENT

Patterning of micro- and nanoscale topologies and surface properties of polymer devices is of particular importance for a broad range of life science applications, including cell-adhesion assays and highly sensitive bioassays. The manufacturing of such devices necessitates cumbersome multiple-step fabrication procedures and results in surface properties which degrade over time. This critically hinders their wide-spread dissemination. Here, we simultaneously mold and surface energy pattern microstructures in off-stoichiometric thiol-ene by area-selective monomer self-assembly in a rapid micro-reaction injection molding cycle. We replicated arrays of 1,843,650 hydrophilic-in-hydrophobic femtolitre-wells with long-term stable surface properties and magnetically trapped beads with 75% and 87.2% efficiency in single- and multiple-seeding events, respectively. These results form the basis for ultrasensitive digital biosensors, specifically, and for the fabrication of medical devices and life science research tools, generally.

In this episode of Made in the USA, several executives and senior staff at Hardinge give their first-person account of how they formulated the plan to shift the manufacturing of its milling and turning product lines from its Taiwan plant to its plant in Elmira, New York, the major challenges they encountered and the rewards that made it worth the effort.

Ever wonder what sets Top Shops apart from the competition? Dive into their award-winning practices and explore behind-the-scenes strategies for operational excellence.

EPTAM Precision Plastics has relied on machine monitoring and benchmarking from Datanomix for years, using it during the early days of the COVID-19 pandemic to optimize production and meet rising demand for semiconductor parts. This success (which we previous covered in 2021) proved to be only the first of many, and EPTAM has continued to implement new Datanomix features to achieve multiple years of 15% year-over-year growth.

Did you know that the show was postponed for WWII? Or that McCormick Place was expanded in the ’70s just to accommodate IMTS? A fascinating look at the show’s history from 1927 to today.

The fabrication method for the silica/TeflonTM mold half requires only one photolithography step, resulting in a self-aligned structural and surface energy micropattern where exposed silica provides hydrophilic surfaces and TeflonTM hydrophobic surfaces (Fig. 1a–e). The molds contain a 5 × 5 matrix of micropillar arrays, with a total of 1,843,650 circular pillars, with diameters in the range of 2.5–4.5 μm, and a centre-to-centre pitch in the range of 7–9 μm (Fig. 1f, g; see Fig. S1 for mold design details). The micropillar heights were in the range 3–4.5 μm. We injected an OSTE-based precursor, containing hydrophobic and hydrophilic chemical moieties, into the mold. During incubation in contact with the mold, the chemical moieties in the polymer network self-assemble on mold surface sections with matching surface energy. Cross-linking of the precursor during a 15 s UV exposure fixates the replica microstructure and its surface energy patterns, after which the replica is demolded. A mold consisting of micropillar arrays thus enables in situ surface energy patterned HIH femtolitre-well arrays with hydrophilic well bottom and sidewalls and hydrophobic interspacing. We observed a high-replication fidelity regarding geometry, size, and defectivity of the microwell arrays during microscopy inspection and optical profiling (Fig. S3). Contact angle measurements on larger planar features substantiate the successful mimicking of surface energy from the molds to the counterpart replica surfaces. The contact angle (CA) of the hydrophobic replica surfaces increases with the incubation time between injection and UV curing, from 90° ± 2.8 for no incubation to 104° ± 2.3 when incubating for 60 min (Fig. S2). The CA of hydrophilic replica surfaces was 59° ± 2.6, independent of the incubation time. The surface energy of the fully cured replicas was re-examined after 11 months storage of the samples in our ambient laboratory conditions (Table S1).

The dynamic range of a digital bioassay is related to the number of microwells, with the demonstrated array size of 105–107 wells theoretically enabling digital target detection with a dynamic range of 6–8 orders of magnitude27. The demonstrated well size and pitch in the µm range are small enough to facilitate integration of large arrays, but large enough for optical detection of individual wells. A mold pillar height/depth aspect ratio of 1/1 results in low-defectivity in terms of pillar collapse while providing a sufficient depth of the wells for trapping beads. For mold pillar aspect ratios >1, the manual and nonvertical demolding led to their occasional collapse.

For established, production-focused machines, however, Bunnell was able to point to a growth in OEE from about 35% to around 60% in a 12-month period. This is shy of EPTAM’s 77% OEE goal, but a massive improvement from where the shop started before adopting Datanomix. As with the “missing operator” downtime insight, Bunnell points to difficulty in fully staffing the facility’s second and third shifts as the primary challenge in maximizing machine utilization.

Zoller’s open house in Ann Arbor, Michigan, provided attendees with a glimpse of the connectivity and efficiency the company’s products offer to users.

Lee Wimmer invited us to tour his second-generation family-owned machine shop in Perkasie, PA. This video explores the production processes behind precision-machined parts for both Wimmer Custom Cycle and LS Wimmer Machine Co., and shows how ingenuity and determination are still at the heart of American manufacturing. Today, both companies are now managed by Wimmer’s three sons.

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Are AMRs the next big trend in job shop automation? System 3R’s IMTS booth will emphasize both its specialty EDM tooling and its automation products, including an autonomous moving robot.

The Walter Turn toolholder features rake-face cooling to help break and control chips, and double flank-face cooling directly at the cutting edge to extend tool life.

Shiu, J.-Y., Aires, L., Lin, Z. & Vogel, V. Nanopillar force measurements reveal actin-cap-mediated yap mechanotransduction. Nat. Cell Biol. 20, 262 (2018).

Most improvements therefore come down to the After Action Report, a feature that enables Bunnell and the EPTAM team to tag machines and jobs that are having trouble reaching their necessary productivity. The system saves the performance of the machine and job as a baseline. From there, the EPTAM team can experiment with machining parameters to see what effects they have on the machining process and whether they enable the job to meet its profitability requirements.

Legacy Precision Molds takes us on a tour of their moldbuilding facility. They've recently implemented two automated 5-axis cells for metal and graphite machining that run lights out during nights and weekends.

AccuRounds has created synergy between culture and technology, driving a commitment to customer satisfaction and continuous improvement.

Though most frequently used for diameter measurements, an air plug and platen can be readily configured to measure perpendicularity.

Weldon Solutions is demonstrating three grinders at IMTS 2024. Though they differ in size and use case, all feature the company’s hallmark customizations.

The RIM platform demonstrated here is adapted for use in laboratory settings, allowing a potential widespread dissemination of the technology. Because life science research typically relies on several tens of identical devices to verify the reproducibility of experiments, the rapid device replication offers an attractive alternative to the manual and error-prone per-part assembly of soft lithography-based devices.

Shafagh, R. Z., Vastesson, A., Guo, W., Wijngaart, Wvander & Haraldsson, T. E-beam nanostructuring and direct click biofunctionalization of thiol–ene resist. ACS Nano 12, 9940–9946 (2018).

Attend TASC, The Automated Shop Conference, in Novi, Mich on Oct. 11, 2023 for a comprehensive look into how to use automation to transform your machine shop.

Wilson, D. H. et al. The simoa hd-1 analyzer: a novel fully automated digital immunoassay analyzer with single-molecule sensitivity and multiplexing. J. Lab. Autom. 21, 533–547 (2016).

Are AMRs the next big trend in job shop automation? System 3R’s IMTS booth will emphasize both its specialty EDM tooling and its automation products, including an autonomous moving robot.

User-friendly inspection software for CNC machining centers is shown monitoring measurements between and after machining while performing SPC based on recorded measurement values.

The unique benefit of our fabrication approach is the simultaneous molding and selective and stable surface energy patterning of microstructures in a single process step, while inheriting all benefits from RIM processing, including short-cycle time, facile processing, low tooling cost of RIM settings along with a surface reactive polymer for additional covalent bonding when fluidic integration is intended. The rapid cycle time, limited mainly by the 15 s UV exposure, constitutes by far the most rapid HIH production method reported. We speculate that the cycle time can be reduced to be on par with the typical standard injection molding cycle times, i.e., 2–5 s, by using a more rigid mold material such as quartz, by a vertical demolding set-up, or by adding more photoinitiator in the polymer precursor.

Datanomix has aided in EPTAM’s automation transition just as it does for the company’s staffed operation. Just as the software provides downtime reasoning for machines, the software can identify where robots stop and why in real time. Bunnell also says After Action Reports work well with robots, establishing functional baselines and enabling the shop to test different process changes to maximize robotic operation and uptime. During the handful of months EPTAM needs to optimize the performance of newly automated cells, the automation engineer works off this data in tandem with manufacturing subject matter experts and the quality team to ensure that production is successful on both efficiency and quality standards.

Kan, C. W. et al. Isolation and detection of single molecules on paramagnetic beads using sequential fluid flows in microfabricated polymer array assemblies. Lab Chip 12, 977–985 (2012).

Formnext Chicago is an industrial additive manufacturing expo taking place April 8-10, 2025 at McCormick Place in Chicago, Illinois. Formnext Chicago is the second in a series of Formnext events in the U.S. being produced by Mesago Messe Frankfurt, AMT – The Association For Manufacturing Technology, and Gardner Business Media (our publisher).

Datanomix’s benchmarking works in tandem with the shop’s quoting software to determine the maximum cycle time on a part that would still result in profitability, then keeps operators aware of how close machines are running to this boundary.

When Puneet and Neelam Neotia moved from India to the United States several years ago, they brought with them a family background in manufacturing and CNC machining. Now the couple is working to get their startup machine shop off the ground, sourcing new customers and getting the word out about their shop in Clarksville, Indiana. The couple — proud to publicize their "Made in the USA" parts — is leveraging family connections and manufacturing capabilities back in India, but not in the way that some people assume.

FANUC’s IMTS 2024 booth includes real-time demonstrations that show the abilities of its equipment, including robots, controllers and machine tools.

FANUC’s IMTS 2024 booth includes real-time demonstrations that show the abilities of its equipment, including robots, controllers and machine tools.

The second mold half consists of the mold insert, i.e., a 0.5 mm thick fused silica mold, also sized 4.5 × 7.4 cm², strengthened with a 2 mm thick piece of borosilicate glass glued to its backside. The fused silica structuring is illustrated in Fig. 1a–e. We started from 0.5 mm thick 4″ fused silica wafers and performed the subsequent steps. We evaporated 250 nm of Cr. We deposited the adhesion promotor Hexamethyldisilazane from the gas phase, spin-coated positive tone photoresist (AZ4533, AZ Electronic materials, Germany), and performed photolithography (Mask aligner, Karl Suss, Germany) with 6 s of UV exposure. We developed the resist in CD-26 Developer (Dow, Rohm-Haas supplier, Germany) for 85 s, followed by hard baking at 115 °C for 120 s, and O2 plasma ashing for 4 min at 150 W. We etched the Cr in a Cr etchant consisting of acetic acid: 3.92% w/w, water: 74.73% w/w, and diammonium cerium(IV) nitrate: 21.35% w/w. We stripped the photoresist and dry etched the wafer with DRIE (STS ICP Multiplex Advanced Oxide Etch) using H2, He and C4F8. We silanized and then teflonized the wafers, in which the silanization acts as an adhesion promoter for the subsequent TeflonTM coating on the fused silica. We prepared a hydrophobic fluoroalkylsilane solution consisting of silane (Dynasylan F8263, Evonik Resource Efficiency GmbH, Essen, Germany): 2% w/w, ethanol: 93% w/w, and water: 5% w/w and spin coated it on the substrate at 3000 rpm for 60 s. We baked the substrates at 110 °C for 12 min. We diluted Teflon AF 1601 (Chemours, USA) with fluorinert FC-40 (Sigma-Aldrich, Germany) with the ratio of 1:6, respectively. We spincoated the Teflon solution on the substrates at 2000 rpm for 60 s, followed by baking at 180 °C for 10 min. A lift-off process was subsequently performed in Cr etchant solution to remove Cr and Teflon from the pillar tops.

Diaz-Quijada, G. A. et al. Surface modification of thermoplastics—towards the plastic biochip for high throughput screening devices. Lab Chip 7, 856–862 (2007).

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Witters, D., Knez, K., Ceyssens, F., Puers, R. & Lammertyn, J. Digital microfluidics-enabled single-molecule detection by printing and sealing single magnetic beads in femtoliter droplets. Lab Chip 13, 2047–2054 (2013).

Part of Major Tool’s 52,000 square-foot building expansion includes the installation of this new Waldrich Coburg Taurus 30 vertical machining center.

Part of Major Tool’s 52,000 square-foot building expansion includes the installation of this new Waldrich Coburg Taurus 30 vertical machining center.

We used an optical profilometer (SENSOFAR S lynx with software SensoSCAN 6.4) for 3D optical cross-sectional imaging of micropillar and microwell arrays.

By automatically gathering data from the machines and sorting it into actionable reports for stakeholders at different levels of management across the facility, Datanomix eliminated a large portion of the legwork associated with data collection and continuous improvement. Bunnell says the greatest challenge the facility has faced with Datanomix is properly conveying to the shopfloor team that this software is meant to support their work, not act as a way to blame operators for any production difficulties.

Researchers from Sweden and Belgium have developed a simplified technique to create microfluidic devices with patterns of modified surface properties. Microfluidic devices, such as the one demonstrated here by a team led by Wouter van der Wijngaart, from KTH Royal Institute of Technology, Sweden, utilize polymer microstructures with hydrophobic and hydrophilic properties to manipulate fluids on a tiny scale. This enables ‘lab-on-a-chip’ experiments with a diverse array of applications. However, current devices suffer from complicated fabrication processes and a limited lifespan. van der Wijngaart and his team used the polymer ‘off-stoichiometric thiol-ene’ to merge a rapid replication technique called reaction injection molding with a method to self-assemble hydrophobic and hydrophilic micropatterns in a single, rapid fabrication step. The researchers hope that their results will form the basis for future microfluidic chip manufacturing and lead to the creation of ultrasensitive life science research tools.

Vergauwe, N. et al. A versatile electrowetting-based digital microfluidic platform for quantitative homogeneous and heterogeneous bio-assays. J. Micromech. Microeng. 21, 054026 (2011).

As a result, EPTAM Precision Plastics has continued to expand a robotic automation initiative it began in 2019 to increase the uptime of its machines. These robots perform a variety of processes from loading and unloading to product conformance verification to in-process deburring.

To demonstrate the hydrophilic nature of the bottoms of the microwells, we isolated fL-sized droplets of an aqueous solution of fluorescein in the microwells and sealed them with oil to prevent evaporation. Visualization of the aqueous fluorescein droplets and the absence of fluorescence at the interspacing surface confirms the HIH nature of the array (Fig. 2).

Weldon Solutions is demonstrating three grinders at IMTS 2024. Though they differ in size and use case, all feature the company’s hallmark customizations.

Heidenhain and Acu-Rite Solutions are offering several hands-on experiences at their booth this year, as well as internal components that reduce energy use.

Miller, M. B. & Tang, Y.-W. Basic concepts of microarrays and potential applications in clinical microbiology. Clin. Microbiol. Rev. 22, 611–633 (2009).

Effective team collaboration is a critical component of success in today’s manufacturing world. With cloud-based technologies that make it easy for team members to brainstorm and problem solve remotely from various locations, design-to-manufacturing processes can become faster and more efficient. This webinar will demonstrate how fully integrated CAM software can be utilized with 3DExperience SolidWorks in a seamless work environment to accelerate product development. Agenda: See how HCL CAMWorks can be used as an add-in for all SolidWorks applications working with the cloud-based 3DExperience platform Learn how fully integrated CAD/CAM saves significant amounts of time during the design to manufacturing process Gain a new understanding of how software can connect users worldwide to accelerate product development Watch a demonstration of team collaboration using platform tools in the CAD/CAM software environment

Faced with rising customer demand for high-precision parts EPTAM Precision Plastics used Datanomix Fusion to streamline data collection, improve quote accuracy and discover training gaps.

New U.S.-based event announced in 2021 finally debuts next year: focuses on complete additive manufacturing value chain. More at formnextchicago.com.

Structured light scanning is used to create a digital twin of a manufactured part, but we must understand the measurement reproducibility to best use the data.

The L.S. Starrett Co. has been manufacturing precision measurement tools in Athol, Massachusetts, since 1880. Attention to U.S. manufacturing often focuses on reshoring manufacturing from other countries, but Starrett never left. The facility in Athol employs hundreds and produces thousands of tools that remain vital for measurement in machining and other fields.

The Automated Shop Conference (TASC) will give shops of all sizes and production volumes key insights and practical guidance on how to implement automation.

Across a range of technical presentations aimed at small and mid-sized job shops, the first-ever Automated Shop Conference (TASC) offered insights into several automated technologies, implementation strategies, shopfloor training tips, and even the untapped power of automated coolant delivery.

From quadruped robot dogs, to an in-booth putting green where you can test out a new golf putter, to a 3D-printed car and more, attendees enjoyed cutting-edge technology and innovations all week long. Take a look to see what (or who!) you might have missed this week!

JD Machine, 2024’s Top Shops Honoree in Human Resources, embodies its “Education for Life” core value with a robust apprenticeship program and significant continuous improvement efforts.

Rob Guiao, Chris Hall and Bassanio Peters will demonstrate relatable situations to equip you with data to improve predictability, future-proof operations and maximize ROI. Agenda:  Explore the importance of data in decision-making, especially for facility upgrades or new projects Learn how comprehensive solutions for manufacturing and construction projects can improve predictability and ROI See real demonstrations of machine integrations, facility layouts and automations to ensure proper throughput and integration

FABTECH 2024 will be held October 15-17, 2024, in Orlando, Florida, at the Orange County Convention Center. FABTECH provides a convenient ‘one-stop shop’ venue where you can meet with world-class suppliers, discover innovative solutions, and find the tools to improve productivity and increase profits. There is no better opportunity to network, share knowledge and explore the latest technology, all here in one place. Future U.S. Show Dates and Locations 2025 – September 8-11 at McCormick Place in Chicago, IL 2026 – October 21-23 at Las Vegas Convention Center in Las Vegas, NV 2027 – September 13-16 at McCormick Place in Chicago, IL

This presentation focuses on the vital role that linear and angular encoders play in ensuring precision in machine tools. Attendees will learn about the common challenges compromising accuracy, such as thermal expansion, mechanical misalignments and vibration. Whether you're an OEM, integrator, or machine operator, this webinar will offer valuable insights into optimizing CNC performance. Agenda: Challenges to CNC machine accuracy Understanding encoder technology How encoders address accuracy challenges

Entrepreneur Scott Colosimo found early success in China producing parts for his Cleveland-based motorcycle company in the mid-2000s. This is the story of how IP theft issues overwhelmed the business, prompting Colosimo and his team to start over from scratch — and move production back to the United States.

Thiol-ene alternating copolymer constitutes an important class of thermosetting materials with a broad range of applications in optics, electronics, and biomedicine19,20. The UV polymerization and click reaction in these polymer networks enable rapid, efficient and by-product free reaction with often no need of solvent use. Also, the delayed gelation in thiol-ene polymerization leads to low shrinkage and low residual stress and enhances replication precision during molding21. Off-stoichiometric thiol-ene (OSTE) imparts additional features such as natively reactive surfaces, which offers a diverse spectrum of applications including adhesive-free bonding22,23 or direct binding of biomolecules24. Hydrophilic and hydrophobic moieties within an OSTE polymer precursor spontaneously self-assemble on areas of a master surface that have matching surface energies25. Sandström et al.26 reported micro-RIM of off-stoichiometric thiol-ene epoxy thermosetting polymers as a rapid processing technique that results in high-replication fidelity and low-residual stress.

We performed CA measurements using a Theta Lite optical tensiometer (TL100, Finland) on non-structured polymer parts replicated from flat, Teflon-coated and bare fused silica molds, respectively. We chose three random areas on each sample and calculated the average CA accordingly. We performed the CA measurements immediately after the RIM process and 11 months after the RIM process measurements to allow measuring surface energy recovery over time.

Dialing in machining parameters and solving for unforeseen difficulties is not just a task EPTAM takes on for new jobs, but also for new machines. The rapid expansion of EPTAM Precision Plastics’ CNC machining fleet from 75 machines to 120 has meant the facility’s OEE has not grown as quickly as its productivity increases would suggest. Bunnell says Datanomix has proved useful for finding machines’ most productive parameters, but continuous improvement staff cannot be everywhere in the shop at once.

Decrop, D. et al. Single-step imprinting of femtoliter microwell arrays allows digital bioassays with attomolar limit of detection. ACS Appl. Mater. interfaces 9, 10418–10426 (2017).

Dressler, O. J., Solvas, X. Ci & deMello, A. J. Chemical and biological dynamics using droplet-based microfluidics. Annu. Rev. Anal. Chem. 10, 1–24 (2017).

In this webinar, industry-leading experts will demonstrate how additive manufacturing can revolutionize your operations and answer the question: Can you afford not to? From rapid prototyping to robust fixturing and specialized custom tooling, it’ll showcase the diverse applications that can drive your business forward in a time where cost and time saving can be crucial. Discover how to reduce costs, accelerate production cycles and achieve unparalleled design freedom through the strategic integration of 3D printing technology. Phillip’s panel of seasoned professionals will share real-world examples and practical insights to help you understand the potential of additive manufacturing. Learn how to overcome production challenges, improve product quality and gain a competitive advantage. It will explore the cost-benefit analysis of 3D printing — including material and labor savings — as well as the potential for increased revenue. Join this webinar to discover why additive manufacturing is no longer a luxury, but a necessity for success. Agenda:  Prototyping example: quick-change prototype Custom tooling real-world example: press brake, tube bending die CMM fixturing and workholding example: CMM fixture and soft jaw

Donzel, C. et al. Hydrophilic poly (dimethylsiloxane) stamps for microcontact printing. Adv. Mater. 13, 1164–1167 (2001).

EPTAM Precision Plastics has achieved multiple years of 15% YoY growth by effectively applying Datanomix’s benchmarking and machine monitoring features.

Lobov, G. S. et al. Electro-optical effects of high aspect ratio p3ht nanofibers colloid in polymer micro-fluid cells. Opt. Lett. 42, 2157–2160 (2017).

When it comes to utilizing the spindle’s power, there is a lot of headroom at the upper limits, provided it’s in short bursts. Be mindful of your time at these loads so you don’t stall out.

Thousands of people visit our Supplier Guide every day to source equipment and materials. Get in front of them with a free company profile.

When EPTAM Precision Plastics first began implementing Datanomix, the Northfield, New Hampshire, facility used about 75 CNC machines to create plastic and metal parts. After several years of rapid expansion, the facility now has 110 CNC machines, 80 of which are connected to Datanomix. Those machines that aren’t connected to Datanomix are older machines that lack Ethernet ports and can’t communicate with the DNC — though the plant plans to swap them out for updated machines compatible with Datanomix over the next few years.

Learn more about the variety of technology and machinery Hwacheon Machinery America, Inc. is featuring at its IMTS 2024 booth.

Sandström, N., Shafagh, R. Z., Gylfason, K. B., Haraldsson, T. & van der Wijngaart, W. Batch fabrication of polymer microfluidic cartridges for qcm sensor packaging by direct bonding. J. Micromech. Microeng. 27, 124001 (2017).

The two mold halves are held together using an Al molding fixture that is 9 mm thick at its base, with sidewalls to align the mold halves. A pair of toggle clamps applies pressure to the mold from above. We attached silicone tubing with an ID of 1.5 mm and OD of 5 mm to the inlet and outlet channels of the mold. Two inlet and outlet ports, embedded into both sides of the Al mold body, enable injection and ventilation prior and during RIM experiment. We initially connected the outlet port to an in-house vacuum source (20 mbar) for degassing the mold cavity and avoiding air entrapment during RIM.

Reinvestment in automation has spurred KCS Advanced Machining Service’s growth from prototyping to low-and mid-volume parts. The key to its success? A young staff of talented programmers.

The latest episode “Made in the USA” podcast explores a company that uses collaborative robots, one of the key tools helping US machine shops and other manufacturers compete with lower cost countries by automating production.

Automatic, real-time shopfloor data collection tempers the bias that blinds manufacturers to the real reasons for downtime.

Job shops are implementing automation and digitalization into workflows to eliminate set up time and increase repeatability in production.