toxic: Poisonous or able to harm or kill cells, tissues or whole organisms. The measure of risk posed by such a poison is its toxicity.

Scientists had known for years that chemicals can leach out of plastic. Some of those chemicals can be toxic. Manufacturers have removed some of the more worrisome chemicals, such as bisphenol A (BPA), from plastic products, such as water bottles. But little is known about what other chemicals might leave these products.

leach: (in geology and chemistry) The process by which water (often in the form of rain) removes soluble minerals or other chemicals from a solid, such as rock, or from sand, soil, bones, trash or ash.

analytical: (in chemistry) A field that focuses on ways to separate materials into their parts or elements or to study the composition of materials.

Christensen, a soccer coach, noticed that players on his team regularly drank water from reusable plastic sports bottles. Sometimes the players complained their water smelled or tasted a bit like plastic. This was usually after the water had been sitting in the bottles for hours. Christensen decided to see if he could figure out why.

Journal:​ J. Peretz et al. Bisphenol A and reproductive health: Update of experimental and human evidence, 2007–2013. Environmental Health Perspectives. Vol. 122, August 1, 2014, p. 775. doi: 10.1289/ehp.1307728.

a PFAS-free alternative to traditional products, supporting manufacturers' sustainability goals and regulatory compliance initiatives;

Journal:​ ​​S. Tisler and J.H. Christensen. Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water. Journal of Hazardous Materials. Vol. 429, May 5, 2022, p. 128331. doi: 10.1016/j.jhazmat.2022.128331.

Lindsey Konkel Neabore likes to write stories about the environment and health for Science News for Students. She has degrees in biology and journalism. She has three cats, Misty, Trumpet and Charlotte, and one dog, Lucky.

They let water sit for 24 hours in new bottles, in used bottles and in bottles that had just come out of a dishwashing machine. Afterward, they used mass spectrometry to test the water. That device can essentially weigh (get the mass) of various chemicals in a sample to identify them. Tisler and Christensen compared what they found in the water from plastic bottles to substances present in water that had been stored in glass.

hormone: (in zoology and medicine) A chemical produced in a gland and then carried in the bloodstream to another part of the body. Hormones control many important body activities, such as growth. Hormones act by triggering or regulating chemical reactions in the body. (in botany) A chemical that serves as a signaling compound that tells cells of a plant when and how to develop, or when to grow old and die.

pollutant: A substance that taints something — such as the air, water, our bodies or products. Some pollutants are chemicals, such as pesticides. Others may be radiation, including excess heat or light. Even weeds and other invasive species can be considered a type of biological pollution.

disrupt: (n. disruption) To break apart something; interrupt the normal operation of something; or to throw the normal organization (or order) of something into disorder.

The Danish team identified some chemicals that are potentially harmful. Future studies could determine how much of each chemical is there, says Kannan. And that’s important, he adds. Just because a chemical is in water doesn’t mean it will cause problems. Much of the risk will depend on how much of a chemical actually gets into the body, he explains.

Two chemists at the University of Copenhagen in Denmark have now used those new analytical tools to study water from sports bottles. Selina Tisler and Jan Christensen now report that these reusable water bottles released hundreds of plastic-related chemicals into the water they held — chemicals that hadn’t been in the starting water. The team describes its findings in the May 5 Journal of Hazardous Materials.

The additive integrates directly into plastic materials and migrates to the surface to facilitate de-molding, helping to reduce cycle times and boost productivity while protecting the mold and manufactured plastic parts. Evoluscend is effective across a range of high-temperature polymers, including PPSU, PES, PSU, PEI, LCP, PPS, and PEEK, said Avient. Furthermore, it can be combined with polymer colorants where color design is desired in a mold-release application.

Pat Hunt does not find the new data surprising. She’s a reproductive biologist at Washington State University in Pullman who has studied plastic leaching. Heat can cause chemicals to migrate out of plastics, she explains. Hot water in a dishwasher helps to clean and sanitize dishes. But plastics that are repeatedly exposed to high heat can start to break down. “Plastics just shouldn’t go in the dishwasher,” she concludes.

Pre-tested to FDA food-contact requirements and ISO 10993 (subparts 4, 5, 10, and 11) requirements for healthcare applications, the Evoluscend mold-release additive for high-temperature polymers is available to manufacturers globally.

In the late 1990s, she found that a hormone-mimicking chemical — BPA — had leached out of the plastic cages and water bottles that she used for the mice in her lab. She had cleaned and sanitized the equipment in a dishwasher. Afterward, BPA (a building block of polycarbonate plastic) tainted the animals’ food and drinking water. Mice exposed to this chemical later had trouble getting pregnant.

environment: The sum of all of the things that exist around some organism or the process and the condition those things create. Environment may refer to the weather and ecosystem in which some animal lives, or, perhaps, the temperature and humidity (or even the placement of things in the vicinity of an item of interest).

Water stored in older plastic bottles contained the highest levels of plastic-related chemicals. Running the bottles through a dishwasher worsened the leaching. After a single wash cycle, more than 3,500 different compounds ended up in a bottle’s water. Many of these were related to dishwasher soap and might remain even after a second rinse. The pollutants appeared to stick more to the plastic bottles than they did to glass ones. Dishwashing also appeared to boost the release of a plastic’s chemicals.

plastic: Any of a series of materials that are easily deformable; or synthetic materials that have been made from polymers (long strings of some building-block molecule) that tend to be lightweight, inexpensive and resistant to degradation. (adj.) A material that is able to adapt by changing shape or possibly even changing its function.

Hunt agrees. “This study represents a starting point,” she says. It gives researchers clues about what chemicals may be present in water from reusable bottles. But it doesn’t reveal what risks the now-polluted water may pose. Indeed, very little is known about many of the chemicals that were detected in the study. More research is needed to learn what these chemicals may do in the body, says Hunt.

risk: The chance or mathematical likelihood that some bad thing might happen. For instance, exposure to radiation poses a risk of cancer. Or the hazard — or peril — itself. (For instance: Among cancer risks that the people faced were radiation and drinking water tainted with arsenic.)

What’s more, until recently, scientists lacked the tools to detect many of the compounds that plastics may shed. New tools now make it possible to detect some of these unknown pollutants, says Kurunthachalam Kannan. He was not involved in the new study. But he’s a chemist at New York University in New York City. For years, he has screened for many such pollutant chemicals in the environment.

More than 400 different compounds had migrated from new plastic bottles into the water. Many were linked to “plasticizers.” These chemicals make the bottles squeezable. Other compounds were slip agents. Manufacturers add these to make plastic products slide easily out of the molds used to shape them. “It’s like how you would oil a baking pan so the cake doesn’t stick to the sides,” explains Tisler. Some chemicals were related to inks. These can give the bottles color or make them look shiny.

Still, Kannan says, lowering exposures to plastic-related chemicals is probably a good idea. He recommends using glass or stainless steel water bottles over plastic when possible.

consumer: (n.) Term for someone who buys something or uses something. (adj.) A person who uses goods and services that must be paid for.

Materials supplier Avient Corp. has introduced a mold-release additive for high-temperature polymers that is formulated without intentionally added per- and polyfluoroalkyl substances (PFAS). The new Evoluscend additive, part of Avient’s Colorant Chromatics portfolio, can be used to enhance the high-pressure injection molding process.

He enlisted the help of Selina Tisler, a scientist in his lab. At the time, she recalls, “We didn’t know what we were looking for.”

Founded in 2003, Science News Explores is a free, award-winning online publication dedicated to providing age-appropriate science news to learners, parents and educators. The publication, as well as Science News magazine, are published by the Society for Science, a nonprofit 501(c)(3) membership organization dedicated to public engagement in scientific research and education.

“If you do use a plastic sports bottle, fill it up and use it right away,” Tisler adds. “It’s best not to store water in them overnight or for long periods of time.”

molecule: An electrically neutral group of atoms that represents the smallest possible amount of a chemical compound. Molecules can be made of single types of atoms or of different types. For example, the oxygen in the air is made of two oxygen atoms (O2), but water is made of two hydrogen atoms and one oxygen atom (H2O).

PFAS chemicals, aka forever chemicals, are used in a broad range of products but have come under scrutiny in recent years for their environmental impact and potential health risks. Globally and domestically, regulatory agencies and legislative bodies are taking steps to reduce or eliminate their use.

Plastic sports bottles shed hundreds of chemicals into the water they hold, a new study finds. The containers release even more pollutants after being run through a dishwasher. Although some of the chemicals might be harmful, it’s not yet known whether there’s any health risk from the amounts that end up in the water.

Editor in chief of PlasticsToday since 2015, Norbert Sparrow has more than 30 years of editorial experience in business-to-business media. He studied journalism at the Centre Universitaire d'Etudes du Journalisme in Strasbourg, France, where he earned a master's degree.

agent: A person or thing (it can be a chemical or even a form of energy) that plays some role in getting something done.

Tisler and Christensen’s study turned up no sign of BPA in the water stored in sports bottles. But some of the chemicals they did detect — including some plasticizers and compounds used to color bottles — may similarly disrupt hormones.

bisphenol A (BPA): A building block of polycarbonate plastics and many commercially important resins. This chemical gained widespread public attention when research showed it could mimic the activity of estrogen, a female sex hormone.

chemical: A substance formed from two or more atoms that unite (bond) in a fixed proportion and structure. For example, water is a chemical made when two hydrogen atoms bond to one oxygen atom. Its chemical formula is H2O. Chemical also can be an adjective to describe properties of materials that are the result of various reactions between different compounds.